F. Y. B. Pharm Semester-I (Term-I)

PCI Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Human Anatomy

&

Physiology-I

BP101T

1

Explain the gross morphology, structure & functions of various organs of the human body.

2

Describe the various homeostatic mechanisms and their imbalances.

3

Identify the various tissues and organs of different systems of human body.

4

Perform the various experiments related to special senses and nervous system.

5

Appreciate coordinated working pattern of different organs of each system.

Human Anatomy

 &

Physiology-I (Practical)

BP107P

1

Demonstrate skills for handling compound microscope.

2

Identify the various tissues and organs of different systems of human body.

3

Perform the various experiments related to special senses & nervous system.

4

Record body temperature.

5

Detail Experiments about Hem cytometry.

Pharmaceutical

Analysis

BP102T

1

Understand the principles of volumetric and electro chemical analysis.

2

Carryout various volumetric and electrochemical titrations.

3

Develop analytical skills.

Pharmaceutical

Analysis
(Practical)

BP108P

1

Prepare and standardize various molar and normal solutions.

2

Carryout various volumetric and electrochemical titrations.

3

Demonstrate analytical skills required for volumetric analysis and electrochemical titrations.

Pharmaceutics -I

BP103P

1

Know the history of profession of pharmacy.

2

Understand the basics of different dosage forms, pharmaceutical incompatibilities and pharmaceutical
calculations.

Pharmaceutics -I

BP109P

1

Prepare various conventional dosage forms such as powders, liquid dosage forms, monophasic and
biphasic liquids.

2

Prepare various conventional dosage forms such as Suppositories & Semisolid dosage forms.

Pharmaceutical
Inorganic
Chemistry

BP104T

1

Know the sources of impurities and methods to determine the impurities in inorganic drugs and
pharmaceuticals.

2

Understand the medicinal and pharmaceutical importance of inorganic compounds.

Pharmaceutical
Inorganic Chemistry (Practical)

BP110P

1

Perform limit test for chlorides, sulphate, iron, heavy metal, lead and arsenic.

2

Perform identification test for magnesium hydroxide, ferrous sulphate, sodium-bicarbonate,
calcium gluconate and copper sulphate.

Communication

Skills

BP105T

1

Understand the behavioral needs for a Pharmacist to function effectively in the areas of pharmaceutical
operation.

2

Communicate effectively (Verbal and Non-Verbal).

3

Effectively manage the team as a team player.

4

Develop interview skills.

5

Develop leadership qualities and essentials.

Communication

Skills

BP111P

1

Demonstrating understanding basic communication like meeting people, asking questions, Do and Don’ts etc.

2

Explain consonant sounds and vowel sounds.

3

Demonstrate understanding of listening comprehension, effective writing skills, interview handling skills
and presentation skills.

Remedial Biology

BP106RBT

1

Know the classification and salient features of five kingdoms of life.

2

Understand the basic components of anatomy & physiology of plant.

3

Know understand the basic components of anatomy & physiology animal with special reference to human.

Remedial Biology
(Practical)

BP112RBP

1

Handle microscope independently.

2

Demonstrate understanding of section cutting techniques, mounting and staining,
permanent slide preparation and identify tissues by microscopic study.

3

Explain stem, root, leaf and its modification.

4

Determine Blood Group, Blood Pressure and Tidal Volume.

5

Study of various Bioassays, Drug antagonism by using computerized simulated software.

Remedial Mathematics

BP106RMT

1

Know the theory and their application in Pharmacy.

2

Solve the different types of problems by applying theory.

3

Appreciate the important application of mathematics in Pharmacy.

F. Y. B. Pharm Semester-II (Term-II)

PCI   Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Human Anatomy

&

Physiology-II

BP201T

1

Explain the gross morphology, structure and functions of various organs of

the human body.

2

Describe the various homeostatic mechanisms and their imbalances.

3

Identify the various tissues and organs of different systems of human body.

4

Perform the hematological tests like blood cell counts, hemoglobin estimation, bleeding/clotting time etc. and also record blood pressure, heart rate, pulse and respiratory volume.

5

Appreciate coordinated working pattern of different organs of each system.

6

Appreciate the interlinked mechanisms in the maintenance of normal functioning (homeostasis) of human body.

Human Anatomy

&

Physiology (Practical)

BP207P

1

Perform the hematological tests like blood cell counts, hemoglobin estimation, bleeding/clotting time etc. and also record blood pressure, heart rate, pulse and respiratory volume.

2

Explain working pattern of different organs of each system.

3

Describe the interlinked mechanisms in the maintenance of normal functioning (homeostasis) of human body.

Pharmaceutical Organic Chemistry–I

BP202T

1

Write the structure, name and the type of isomerism of the organic compound.

2

Write the reaction, name the reaction and orientation of reactions.

3

Account for reactivity/stability of compounds, identify/confirm the identification of organic compound.

Pharmaceutical Organic Chemistry–I (Practical)

BP208P

1

Identify/confirm the identification of organic compound.

2

Explain construction of molecular models.

Biochemistry

BP203T

1

Understand the catalytic role of enzymes, importance of enzyme inhibitors in

design of new drugs, therapeutic and diagnostic applications of enzymes.

2

Understand the metabolism of nutrient molecules in physiological and pathological conditions.

3

Understand the genetic organization of mammalian genome and functions of

DNA in the synthesis of RNA’s and proteins.

Biochemistry
(Practical)

BP209P

1

Perform Qualitative analysis of carbohydrates, reducing sugars and Proteins, urine

for abnormal constituents.

2

Determine blood creatinine, sugar, cholesterol.

3

Prepare buffer solution and measure pH.

4

Estimate Salivary Amylase activity and study different factors like temperature, substrate.

Pathophysiology

BP204T

1

Describe the etiology and pathogenesis of the selected disease states.

2

Name the signs and symptoms of the diseases.

3

Mention the complications of the diseases.

Computer Applications In Pharmacy

BP205T

1

Know the various types of application of computers in pharmacy.

2

Know the various types of databases.

3

Know the various applications of databases in pharmacy.

Computer Applications In Pharmacy

(Practical)

BP210P

1

Design a questionnaire using a word processing package to gather information

about a particular disease.

2

Create a HTML web page to show personal information.

3

Retrieve the information of a drug and its adverse effects using online tools.

4

Create mailing labels Using Label Wizard, generating label in MS WORD.

5

Create a database in MS Access to store the patient information with the required

fields Using access. Generating report and printing the report from patient database.

6

Design a form in MS Access to view, add, delete and modify the patient record in the database.

7

Creating invoice table, Drug information storage and retrieval, Creating and

working with queries using MS Access.

8

Exporting Tables, Queries, Forms and Reports to web pages and XML pages.

Environmental

Sciences

BP206T

1

Create the awareness about environmental problems among learners.

2

Impart basic knowledge about the environment and its allied problems.

3

Develop an attitude of concern for the environment.

4

Motivate learner to participate in environment protection and environment improvement.

5

Acquire skills to help the concerned individuals in identifying and solving

environmental problems.

6

Strive to attain harmony with Nature.

S. Y. B. Pharm Semester-III (Term-I)

PCI   Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Pharmaceutical Organic Chemistry–II

BP301T

1

Write the structure, name and the type of isomerism of the

organic compound.

2

Write the reaction, name the reaction and orientation of reactions
.

3

Account for reactivity/stability of compounds.

4

Prepare organic compounds.

Pharmaceutical Organic Chemistry–II (Practical)

BP305P

1

Determine analytical constants of fats and oils.

2

Carry out preparation of organic compound and purify by recrystallization,

steam distillation.

3

Explain principle, mechanism and procedure of synthesis of given

organic compound.

4

Calculate theoretical yield, practical yield and percentage yield
.

Physical Pharmaceutics-I

(Theory)

BP302T

1

Understand various physicochemical properties of drug molecules

in the designing the dosage forms.

2

Know the principles of chemical kinetics & to use them for stability testing and determination of expiry date of formulations.

3

Demonstrate use of physicochemical properties in the formulation development

and evaluation of dosage forms.

Physical Pharmaceutics-I

(Practical)

BP306P

1

Estimate Solubility and Distribution Phenomenon of drug.

2

Illustrate Surface & interfacial phenomenon including adsorption

in stability of biphasic dosage form.

3

Apply the Concept of Hydrophilic Lipophilic Balance & Critical

Micellar Concentration in practical aspects.

4

Analyze the complex formation by solubility & pH titration method.

Pharmaceutical Microbiology

(Theory)

BP303T

1

To understand the importance and implementation of

sterilization in pharmaceutical processing and industry.

2

Learn sterility testing of pharmaceutical products.

3

Carry out microbiological standardization of Pharmaceuticals.

4

Understand the cell culture technology and its applications in

pharmaceutical industries.

Pharmaceutical Microbiology

(Practical)

BP307P

1

To demonstrate the use of various equipment’s and their processing used in experimental microbiology.

2

To describe the process of sterilization and sub culturing.

3

To illustrate different staining techniques and motility

determination by hang drop method.

4

To prepare media, nutritional stabs & slants and pure culture of

microorganisms.

5

To perform sterility and biochemical test, microbiological assay and
bacteriological analysis.

Pharmaceutical Engineering

(Theory)

BP304T

1

To know various unit operations used in pharmaceutical industries.

2

To understand the material handling techniques.

3

To perform various processes involved in pharmaceutical manufacturing process.

4

To carry out various test to prevent environmental pollution.

5

To appreciate and comprehend significance of plant lay out design for optimum use

of resources.

6

To appreciate the various preventive methods used for corrosion

control in Pharmaceutical industries.

Pharmaceutical Engineering

(Practical)

BP308P

1

Determine radiation constant, heat transfer coefficient, moisture

content, loss of drying & humidity of air.

2

Calculate efficiency of steam distillation & uniformity of index.

3

Construct drying curves & study the effect of time on the rate of crystallization.

4

Evaluate size distribution & verify the laws of size reduction by determining

various parameters related to Ball mill.

5

Demonstrate major equipment’s used in pharmaceutical industry.

6

Discuss construction working & applications of pharmaceutical

machinery & factors affecting rate of filtration & evaporation.

S. Y. B. Pharm Semester-IV (Term-II)

PCI   Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Pharmaceutical Organic Chemistry–III (Theory)

BP401T

1

Understand the methods of preparation and properties of organic compounds.

2

Explain the stereo chemical aspects of organic compounds and stereo chemical reactions.

3

Know the medicinal uses and other applications of organic compounds.

Medicinal Chemistry–I (Theory)

BP402T

1

Understand the chemistry of drugs with respect to their pharmacological activity.

2

Understand the drug metabolic pathways, adverse effect and therapeutic value of drugs.

3

Know the Structural Activity Relationship (SAR) of different class of drugs.

4

Write the chemical synthesis of some drugs.

Medicinal Chemistry–I (Practical)

BP406P

1

Synthesize drugs.

2

Carry out assay of drugs.

3

Determine partition coefficient of drug.

Physical Pharmaceutics-II

(Theory)

BP403T

1

Understand various physicochemical properties of drug molecules in the designing the dosage forms.

2

Know the principles of chemical kinetics & to use them for stability testing  and determination of expiry date of formulations.

3

Demonstrate use of physicochemical properties in the formulation development and evaluation of dosage forms.

Physical Pharmaceutics-II

(Practical)

BP407P

1

Estimate particle size, Particle size distribution & Flow rate of powder by using micrometrics principles.

2

Analyze flow properties of liquid by rheological measurements.

3

Evaluate properties of coarse dispersion using various parameters.

4

Analyze the drug stability by applying principles of chemical kinetics.

Pharmacology-I

(Theory)

BP404T

1

Understand the pharmacological actions of different categories of drugs.

2

Explain the mechanism of drug action at organ system/sub cellular/ macromolecular levels.

3

Apply the basic pharmacological knowledge in the prevention and treatment of various diseases.

4

Observe the effect of drugs on animals by simulated experiments.

5

Appreciate correlation of pharmacology with other bio medical sciences.

Pharmacology-I

(Practical)

BP408P

1

Understand the pharmacological actions of different categories of drugs.

2

Explain the mechanism of drug action at organ system/sub cellular/ macromolecular levels.

3

Apply the basic pharmacological knowledge in the prevention and treatment of various diseases.

4

Observe the effect of drugs on animals by simulated experiments.

5

Appreciate correlation of pharmacology with other bio medical science.

Pharmacognosy

&

Phytochemistry- I

 (Theory)

BP405T

1

To know the techniques in the cultivation and production of crude drugs.

2

To know the crude drugs, their uses and chemical nature.

3

Know the evaluation techniques for the herbal drugs.

4

To carry out the microscopic and morphological evaluation of crude drugs.

Pharmacognosy

&

Phytochemistry- I (Practical)

BP409P

1

Introduce the students to carry out chemical evaluation of natural drugs used in complimentary system of medicine.

2

Highlights the microscopic qualitative and quantitative evaluation of powdered crude drugs of natural origin.

3

Understand principles involved and carry out physical evaluation of natural crude drug powders.

T. Y. B. Pharm Semester-V (Term-I)

CBCS   Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Organic 

Chemistry III

BPH_C_501_T

1

Identify, nomenclate, and to employ fundamental heterocyclic organic

reactions in the synthetic design of biologically active molecules

containing heterocyclic nucleus.

2

Recognize the steroid molecules, synthetic methods, nature and their

role in our body.

3

Outline the synthesis, chemical reactions of steroids, conversion of cholesterol

to progesterone, estrone and testosterone and elucidation of structure of cholesterol.

4

State basic terminologies in polymers, different mechanisms involved in the polymer preparation, different polymerization techniques, details about the glass transition temperature and the factors affecting it and the types of polymers with some specific examples of each.

Organic Chemistry Lab II

BPH_C_505_L

1

To carry out the separation of simple compound mixtures.

2

To identify organic compounds based on simple tests.

3

To recrystallize compounds use single solvent and binary solvent mixtures.

Pharmaceutics II

BPH_C_502_T

1

Understand the formulation of liquid biphasic, semisolid, suppository and

aerosol dosage forms.

2

Describe the evaluation of such dosage forms.

3

Summarize the packaging of liquid biphasic, semisolid, suppository and

aerosol dosage forms.

4

Explain the basic concepts of cosmetic science.

Pharmaceutics

Lab II

BPH_C_506_L

1

Understand the formulation aspects of biphasic and semisolid dosage forms.

2

Explain calculations involved in formulations.

3

Describe the importance of quality evaluation of biphasic, semisolids,

suppositories, aerosols.

Pharmaceutical

Biotechnology

BPH_C_503_T

1

To discuss the tools, techniques, ethics and environmental safety involved in

gene cloning, and the applications of Recombinant DNA technology

2

Discuss basics of immunology and explain the antigen-antibody interactions and defense mechanism and explain technique of monoclonal antibodies production

for treating the human diseases.

3

Study fermentation technology and understanding the basic concepts for

production of safer vaccines and antibiotics.

4

To study different techniques and applications of microbiological assay, enzyme immobilization and cell culture.

Experimental

Techniques in

Microbiology and

Biotechnology Lab

BPH_C_507_L

1

Characterization and identification of bacteria using various staining techniques (morphological study), colony characterization, serological and biochemical characteristics.

2

Analyze quality of raw material, food and water and assessment of extent of

microbial contamination using counting technique and evaluate sterility of products.

3

To impart the knowledge of bioassay of antibiotic and test antibiotic sensitivity

of few antibiotics.

Pharmacology II

BPH_C_504_T

1

Discuss pharmacology of drugs used in chemotherapy and justify the need for

rational use of antimicrobials.

2

Explain pharmacology of drugs used as immunomodulators.

3

Explain pharmacology of drugs used in endocrine disorders & hematological disorders.

Nutraceuticals And Dietary Supplements

BPH_E_508_T

1

Explain concept of nutraceuticals and dietary supplements, classify these

based on chemical nature, health benefits and mechanism of action.

2

Discuss the chemistry of phytochemicals, their health benefits, pharmacokinetics, interactions with food and recommended doses along with the marketed preparations.

3

Explain the challenges in formulating nutraceuticals.

4

Understand the significance of safety and stability studies of nutraceuticals.

5

Describe the labeling and regulatory aspects for manufacture and sale of

nutraceutical products.

Microbial Genetics

BPH_E_509_T

1

Understand basic concepts of homologous recombination and genetic exchange

among prokaryotes.

2

Understand natural plasmids and transposons present in prokaryotes.

3

Give an account of prokaryotic gene structure and the mechanisms controlling

gene expression.

Biochemistry III

BPH_E_510_T

1

Explain how DNA topology and chromatin structure affects the processes of

DNA replication, repair, and transcription.

2

Compare and contrast the mechanisms of bacterial and eukaryotic

DNA replication, transcription, and translation.

3

Describe mechanisms by which DNA can be damaged, mutated and describe

the molecular mechanisms by which protein complexes repair different forms

of DNA damage.

4

Explain the molecular mechanisms behind different modes of gene regulation

in bacteria.

Synthon Approach

BPH_E_511_T

1

Learner will also gain confidence for drawing the schematic retrosynthetic

pathway from the course.

2

Learner will be able to analyze the retrosynthetic scheme synthesis planning

and route analysis for any given target molecule.

Cosmetic ology

BPH_E_512_T

1

Discuss the various raw materials for cosmetics.

2

Understand the toxicological aspects and toxicity testing for cosmetics.

3

Discuss the various cosmetics products w.r.t. raw materials, large

scale manufacturing and functional and physicochemical evaluation.

4

Know the regulatory guidelines and sensorial assessment for cosmetics.

Packaging of

Pharmaceuticals

BPH_E_513_T

1

Classify Packaging materials and explain the functions and design aspects.

2

Discuss the different primary and ancillary packaging materials, their functions

and evaluation.

3

Elaborate on labelling aspects of pharmaceuticals.

4

Discuss sterilization and stability of packaging materials.

T. Y. B. Pharm Semester-VI (Term-II)

CBCS   Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Pharmaceutical

Chemistry I

BPH_C_601_T

1

Identify and study the suitable drug targets for treatment of disorders.

2

Identify the relationship between the physicochemical properties of

the chemical entity and biological response.

3

Draw a schematic metabolic pathway for any given drug.

4

Identify the SAR of all the classes of antimalarial, antitubercular, anti-infective, antibiotic, antiparasitic disorders.

Pharmaceutical Chemistry

Lab I

BPH_C_605_L

1

Understand the synthesis of drugs.

2

Know the difference between conventional synthesis and green chemistry approach.

3

To know the medicinal uses and applications of drugs synthesized.

Pharmaceutics III

BPH_C_602_T

1

Know the various solid oral dosage forms and their manufacturing technique.

2

Know various considerations in development of pharmaceutical dosage forms

including stability.

3

Formulate solid dosage forms and evaluate them for their quality.

4

Understand the responsibilities of quality assurance & quality control departments.

5

Appreciate the importance of documentation.

Pharmaceutics

Lab III

BPH_C_606_L

1

Formulate solid dosage forms like tablets and capsules and evaluate them for

their quality.

2

Understand the tablet coating process.

3

Learn the concepts of accelerated stability testing and shelf life calculations.

Pharmaceutical

Analysis II

BPH_C_603_T

1

Comprehend underlying principle, instrumentation, application and limitations in instrumental techniques involving molecular as well as atomic absorption and

emission techniques such as UVVisible, Fluorescence, Infra-Red, Raman, Atomic absorption spectroscopy and Atomic emission spectroscopy.

2

Explain fundamentals, working principle and applications of X-ray diffraction

technique, potentiometric titrations and thermal methods of analysis like TG,

DSC and DTA.

3

Generalize the concepts and quality control aspects related to radiopharmaceuticals.

4

Calculate and interpret the results for spectral analysis and statistical data analysis.

Pharmaceutical

Analysis Lab II

BPH_C_607_L

1

Record the absorbance and calculate concentration of analyte in formulation or

as an API by use of A(1%, 1cm), single point and double point standardization by

UV spectrophotometer.

2

Relate and construct linear regression analysis data for colorimetric assays and

operate a colorimeter instrument.

3

Record and calculate the concentration of an analyte by measure

of fluorescence of an analyte in absence and presence of quenching agent.

4

Operate a pH meter, measure equivalence point by potentiometric titration,

calculate pKa and normality for a given acid or mixture of acids.

5

Understand the sample preparation technique for FTIR spectroscopy,

interpret the IR spectra to identify the functional groups of an analyte, and

understand the working of a flame photometer.

Pharmacognosy II

BPH_C_604_T

1

Extraction of phytoconstitutents, concept of adulteration and substitution.

2

Utility of natural products as excipients utilized in pharmaceutical preparations.

3

Applications of plant tissue culture techniques for production of secondary

metabolites and edible vaccines.

4

To introduce the learner to the chemistry, sources, cultivation and collection of

crude drugs containing phytoconstituents like volatile oils, resins and tannins.

5

To introduce the learner to the biosynthesis of volatile oil constituents belonging

to the classes of monoterpenoids and phenylpropanoids.

6

To make the learner understand the chemistry of phytoconstituents belonging to the classes of iridoids, sesquiterpenes, diterpenes, tetraterpenes and sulphur containing compounds along with sources and utility of representative examples of crude drugs in therapeutics.

Pharmaceutical

Management

BPH_E_608_T

1

Study and interpret companies’ financial statements & its components.

2

State the importance of marketing in the pharma industry.

3

Outline the basic principles of management.

4

Discuss the importance of management in quality control & government regulation.

Biopharmaceutics

and

Pharmacokinetics

BPH_E_609_T

1

Explain the basic terms used in Biopharmaceutics and Pharmacokinetics.

2

Understand the concept of pharmacokinetics models and significance of

various pharmacokinetic parameters.

3

Understand BCS Classification, theories of Dissolution and methods of

dissolution testing.

4

Explain the concepts of Bioavailability and Bioequivalence and IVIVC.

5

Solve problems based on principles of Pharmacokinetics.

Basic Principles of

Toxicology

BPH_E_610_T

1

Define toxicological terms mentioned in the course.

2

Discuss mechanism of toxicity, factors influencing toxicity and management of poisoning.

3

Explain metal poisoning and basic principles with suitable example of drug

induced toxicity.

4

Discuss in brief about different types of toxicity test.

5

Demonstrate the knowledge of regulatory toxicology and able to apply this

knowledge for design of nonclinical toxicology and clinical development of drugs.

Cell and Tissue

Culture

BPH_E_611_T

1

Understand the basic requirements of cell and tissue culture.

2

Plan experiments using cultured cells.

3

Carry out cell culture, and associated laboratory techniques.

4

Explore the concepts of cell and tissue culture in production of pharmaceutical products.

Pharmaceutical

Process Chemistry

and Technology

BPH_E_612_T

1

Describe the basic concepts of process chemistry and process development.

2

Describe the basic concepts of process chemistry and process development.

3

Outline the regulatory guidelines related to API manufacturing.

4

Appreciate the importance of safety in pharmaceutical industry.

Pharmaceutical

Excipients

BPH_E_613_T

1

Define, classify and elaborate on regulatory aspects of Pharmaceutical excipients.

2

Understand the characterization and interactions of excipients with APIs

and packaging materials.

3

Elaborate on common and novel excipients in Pharmaceuticals.

4

Explain the role of polymers as excipients.

Final Y. B. Pharm Semester-VII (Term-I)

CBCS   Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Pharmaceutical

Chemistry II

BPH_C_701_T

1

In the thrust areas chemotherapy for cancer, antiviral diseases, cardiovascular

drugs like antianginal agents, antiarrhythmic agents, diuretics, drug affecting

the RAS pathway, vasodilators, antihyperlipidemic agents.

2

They will be apply this knowledge in research areas.

Pharmacognosy III

BPH_C_702_T

1

Write the source, composition, general methods of extraction, evaluation, chemical tests, therapeutic uses of crude drugs containing phytoconstituents like steroidal, triterpenoidal, anthraquinone, flavonoidal glycosides, alkaloids glycoproteins.

2

Write the biosynthesis of biosynthesis of alkaloids obtained from different amino acids.

3

Understand regulatory requirements for manufacture and sale of Ayurvedic Siddha

and Unani (ASU) Medicines and Phytopharmaceuticals, monographs of herbal drugs.

4

Apply the knowledge of excipients from natural origin and pharmaceutical technology

to herbal formulation and understand the challenges in herbal formulation.

5

Understand the concept of herbal drug standardization and its application to

herbal formulation.

6

Apply the knowledge of pharmacology to understand pharmacodynamic and pharmacokinetic interactions of herbal drugs with food.

Pharmacognosy Lab II

BPH_C_706_L

1

Identify crude drugs based on morphological characters, microscopic characters and give biological source with the chemical constituents and therapeutic uses.

2

Apply the knowledge of microscopic characters in ascertaining the genuinely of powdered formulations.

3

Extract and perform qualitative chemical rests on the crude drugs containing Anthraquinonoid Glycosides, Cardiac Glycosides, Flavonoids, Cyanogenetic Glycosides, Alkaloids, Triterpenoid and Steroidal Glycosides, Saponins, Tannins.

4

Apply analytical procedures and principles for quantitative determination of

total Aldehyde content / Phenol content / total alkaloids from crude drugs.

5

Understand principles involved apply these for carrying out extraction of active constituents.

6

Identify crude drugs based on the morphological characters and quote some formulations available in market with their therapeutic utility.

Pharmaceutical

Analysis III

BPH_C_703_T

1

Explain various methods used for multicomponent analysis of drugs by UV spectroscopy.

2

Summarize chromatographic and hyphenated techniques used for the

separation, identification and quantification of analytes.

3

Describe the working of proton 1H NMR spectroscopy and mass spectrometry.

4

Interpret spectral data to predict structure of a given compound.

5

Summarize the parameters of ICH guidelines for analytical method validation.

Pharmaceutical

Analysis Lab III

BPH_C_707_L

1

Record, calculate and interpret data obtained by UV spectrophotometric analysis

for pKa determination and concentration determination by multicomponent

analysis techniques.

2

Apply ICH guidelines to validate an analytical method by UV spectroscopy and

interpret results obtained.

3

Develop and optimize mobile phase composition for qualitative analysis by TLC

and interpret qualitative analysis data by TLC and paper chromatography.

4

Outline working and application of column chromatography, HPLC and GC.

Pharmacology III

BPH_C_704_T

1

Explain pharmacology of drugs acting on central nervous system and associated diseases.

2

Classify and explain pharmacology of anti-inflammatory drugs, make use of

knowledge of these drugs to justify their use in asthma and gout.

3

Discuss the pharmacology of drugs used in gastrointestinal disorders.

4

Know the toxic effects of heavy metals, drugs and environmental toxicants.

Pharmacology

Lab II

BPH_C_708_L

1

Define Bioassay, list the types, methods and applications of bioassay and perform in vitro bioassay using cock ileum and record, calculate and interpret unknown concentration of agonist/antagonist/drug.

2

Observe preclinical models which provide evidences on drug/lead

pharmacological activity.

3

Relate to and apply the ethical, regulatory and toxicity guidelines/rules (ICH, OECD, CPCSEA, Schedule Y) in drug/lead testing using preclinical animals.

Pharmaceutical

Jurisprudence

BPH_C_705_T

1

Interpret Pharmaceutical Legislation.

2

Understand pricing of drugs & pharmaceuticals.

3

Summarize offences & penalties concerned with laws for drugs and pharmaceuticals.

4

Gain an insight into Drug Regulatory Affairs.

Intellectual Property

Rights

BPH_E_709_T

1

Correlate the knowledge of IPR with respect to pharmaceutical products.

2

Apply knowledge of IPR in designing strategy for pharmaceutical product development.

Green Chemistry &

Catalysis

BPH_E_710_T

1

Know the terms involved in green chemistry.

2

Understand the concept and techniques of waste management.

3

Know various guidelines of environmental management system.

4

Outline type of catalysis and their uses.

5

Learn greener process designing.

Pre formulation

Studies

BPH_E_711_T

1

Explain physicochemical principles relevant to pharmaceutical dosage forms.

2

Comprehend the importance of solubility, stability and compatibility of drug substances with different excipients.

3

Understand the role of pre formulation studies in drug discovery, drug and

product development.

Final Y. B. Pharm Semester-VIII (Term-II)

CBCS   Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Pharmaceutical

Chemistry III

BPH_C_801_T

1

In the thrust areas of CNS, ANS active drugs, analgesic agents and male female hormones.

2

They will be apply this knowledge in research areas.

Pharmaceutical

Chemistry Lab II

BPH_C_803_L

1

Design and perform various unit operations of organic synthetic reactions.

2

Characterize reaction intermediates and final products.

3

Know the theoretical concepts behind organic synthesis.

4

Understand the concept and techniques of waste management.

Pharmaceutics IV

BPH_C_802_T

1

Apply the knowledge of sterile technology in designing safe and effective

injectable and ophthalmic products.

2

Study the rationale for oral SR/CR products, principles of design, development

and evaluation of SR formulations.

3

Understand the concepts of validation and pilot plant scale up for large scale manufacturing operations.

4

Understand the concept of biopharmaceutics and significance of various pharmacokinetic parameters.

Pharmaceutics

Lab IV

BPH_C_804_L

1

Demonstrate the intricacies of formulation and development of parenteral

and ophthalmic products.

2

Understand and know about quality control and documentation of

a manufacturing process.

3

Know about the pharmacopoeial tests for these products and their packaging materials.

4

Explain the concept of dissolution testing as an important quality control tool

and relate to its importance from regulatory point of view.

5

Apply pharmacokinetic principles of oral routes of administration.

6

Demonstrate oral and written communication skills and ability to plan the experimentation with proper time management.

Phytopharmaceutical

Technology

BPH_E_806_T

1

Understand terms related to phytopharmaceuticals and standardization of

Natural Products.

2

Explain industrial preparation of standardized extracts, isolation of

phytoconstitutents and their applications.

3

Discuss the challenges faced in formulation of conventional and NDDS of

herbal medicines.

4

Explain the applications of QC and QA of Phytopharmaceuticals.

5

To suggest the use of herbs as nutraceuticals in common disorders and

cosmeceuticals.

Clinical Pharmacy

BPH_E_807_T

1

Relate to the role of pharmacist in different setups like clinics, pharmacies & in

the community and appraise the crucial role of pharmacists in patient counselling

and eventually in drug adherence and compliance to therapy.

2

Discuss the types, risk factors, classification, methods of detection, monitoring

and reporting of ADRs, drug interactions, pharmacovigilance and TDM in normal

as well as special populations.

3

Outline the process of drug discovery and development, Ethical Guidelines/Schedules, Role of Ethics Committee, essential documents in clinical trials/research, BA-BE studies and, apply and appreciate the role of GCP in conduct of clinical research.

4

Identify and analyze the trends in drug use to optimize health outcomes.

Pharmacovigilance

BPH_E_808_T

1

Relate to the role of pharmacovigilance and its prevalence in different setups.

2

Discuss the different facets of ADRs in normal as well as special populations with

their relation to pharmacovigilance methods.

3

Integrate knowledge of resources of drug information, safety data and drug utilization.

4

Outline the regulatory processes in pharmacovigilance.

Pharmaceutical

Regulatory Affairs

BPH_E_809_T

1

Understand the basics of new drug and generic product development.

2

Apply knowledge of regulatory requirements for preparing the documents for registration of pharmaceutical product in India and overseas.

3

Understand various harmonized practices and integrate the knowledge required

for various certifications.

Lead Optimization –

Strategies and

Methods

BPH_E_810_T

1

Understand the importance of druggability and physicochemical/ADME/Toxicity property optimization in new drug discovery.

2

Understand the fundamentals of various physicochemical and pharmacokinetic properties and their significance in lead optimization.

3

Know various strategies for structure modification for optimizing drug ability of lead molecules.

4

Describe different methods of determination of various physicochemical and pharmacokinetic properties of lead compounds.

Novel Drug Delivery

Systems

BPH_E_811_T

1

Understand the basic concept of NDDS.

2

Discuss the different NDDS for different routes-oral, transdermal, ocular, transmucosal and implantable.

3

Explain the need and concepts of targeting and active & passive targeting.

4

Elaborate on principles and targeting systems for brain, colon, lymphatics and tumors.

5

Discuss the various multiparticulate systems for targeting.

F. Y. M. Pharm Semester-I (Term-I)

PCI Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Modern Pharmaceutical Analytical Techniques

MPH 101T

1

Chemicals and Excipients.

2

The analysis of various drugs in single and combination dosage forms.

3

Theoretical and practical skills of the instruments.

Drug Delivery Systems

MPH 102T

1

The various approaches for development of novel drug delivery systems.

2

The criteria for selection of drugs and polymers for the development of delivering system.

3

The formulation and evaluation of Novel drug delivery systems.

Modern Pharmaceutics

MPH 103T

1

The elements of pre formulation studies.

2

The Active Pharmaceutical Ingredients and Generic drug Product development.

3

Industrial Management and GMP Considerations.

4

Optimization Techniques & Pilot Plant Scale Up Techniques.

5

Stability Testing, sterilization process & packaging of dosage forms.

Pharmaceutics Practical’s -I

MPH 105T

1

After completion of course student is able to know, Practical skills of the instruments

& analysis of various drugs in single & combination dosage form.

2

The criteria for selection of drugs & polymers for the development of delivery system.

3

The formulation & evaluation of Novel drug delivery system.

4

The kinetic modelling of dissolution profiles & compare dissolution profiles.

Regulatory Affaires

MPH 104T

1

The Regulatory guidance’s and guidelines for filing and approval process.

2

Preparation of Dossiers and their submission to regulatory agencies in different countries.

3

Post approval regulatory requirements for actives and drug products.

4

Submission of global documents in CTD/ eCTD formats.

5

Clinical trials requirements for approvals for conducting clinical trials.

6

Pharmacovigilance and process of monitoring in clinical trials.

F. Y. M. Pharm Semester-II (Term-II)

PCI   Syllabus

COURSE

COURSE CODE

CO NO.

COURSE

Upon completion of this course the student should be able to:

Molecular Pharmaceutics

 (Nano Technology & Targeted DDS) (NTDS)

MPH 201T

1

The various approaches for development of novel drug delivery systems.

2

The criteria for selection of drugs and polymers for the development of NTDS.

3

The basic concepts in biopharmaceutics and pharmacokinetics.

Advance Biopharmaceutics

& Pharmacokinetics

MPH 202T

1

The basic concepts in biopharmaceutics and pharmacokinetics.

2

The use raw data and derive the pharmacokinetic models and parameters the best describe the process of drug absorption, distribution, metabolism and elimination.

3

The critical evaluation of biopharmaceutics studies involving drug product equivalency.

4

The design and evaluation of dosage regimens of the drugs using pharmacokinetic

and biopharmaceutics parameters.

5

The potential clinical pharmacokinetic problems and application of basics of pharmacokinetic.

Computer Aided Drug Development

MPH 203T

1

History of Computers in Pharmaceutical Research and Development.

2

Computational Modeling of Drug Disposition.

3

Computers in Preclinical Development.

4

Optimization Techniques in Pharmaceutical Formulation.

5

Computers in Market Analysis.

6

Computers in Clinical Development.

7

Artificial Intelligence (AI) and Robotics.

8

Computational fluid dynamics (CFD).

Cosmetics & Cosmeceuticals

MPH 204T

1

Key ingredients used in cosmetics and cosmeceuticals.

2

Key building blocks for various formulations.

3

Current technologies in the market.

4

Various key ingredients and basic science to develop cosmetics and cosmeceuticals.

5

Scientific knowledge to develop cosmetics and cosmeceuticals with desired Safety, stability, and efficacy.

Pharmaceutics Practices – II (Practical)

MPH 205P

1

The criteria for selection of drugs & polymers for the development of Novel

Targeted Delivery Systems.

2

The formulation & evaluation of Novel Drug Delivery Systems.

3

The formulation & evaluation of Cosmetics & Cosmeceuticals.

4

The application of various software’s such as DOE, WinNonline & other.